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      For those who want a super quick summary, this update from Katelyn
      Jetelina is mostly good news with trends toward fewer COVID
      issues, but we are not out of the woods.--Manny<br>
      <br>
      <pre class="moz-signature" cols="72">"Failure is unimportant. It takes courage to make a fool of yourself."
— Charlie Chaplin</pre>
      <div class="moz-forward-container"><br>
        <br>
        -------- Forwarded Message --------
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          cellpadding="0" border="0">
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              <th valign="BASELINE" nowrap="nowrap" align="RIGHT">Subject:
              </th>
              <td>Catch up quick: COVID-19</td>
            </tr>
            <tr>
              <th valign="BASELINE" nowrap="nowrap" align="RIGHT">Date:
              </th>
              <td>Thu, 25 May 2023 11:15:07 +0000</td>
            </tr>
            <tr>
              <th valign="BASELINE" nowrap="nowrap" align="RIGHT">From:
              </th>
              <td>Katelyn Jetelina from Your Local Epidemiologist <a
                  class="moz-txt-link-rfc2396E"
                  href="mailto:yourlocalepidemiologist@substack.com"
                  moz-do-not-send="true"><yourlocalepidemiologist@substack.com></a></td>
            </tr>
            <tr>
              <th valign="BASELINE" nowrap="nowrap" align="RIGHT">Reply-To:
              </th>
              <td>Katelyn Jetelina from Your Local Epidemiologist
                <a class="moz-txt-link-rfc2396E"
href="mailto:reply+21bpx0&a13t&&61b16c1eae747b646e4e4dc47af520fb8b57f47159ba3b02d8d30a0c5ab9b62c@mg1.substack.com"
                  moz-do-not-send="true"><reply+21bpx0&a13t&&61b16c1eae747b646e4e4dc47af520fb8b57f47159ba3b02d8d30a0c5ab9b62c@mg1.substack.com></a></td>
            </tr>
            <tr>
              <th valign="BASELINE" nowrap="nowrap" align="RIGHT">To: </th>
              <td><a class="moz-txt-link-abbreviated"
                  href="mailto:manny@ratafias.com"
                  moz-do-not-send="true">manny@ratafias.com</a></td>
            </tr>
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        <title>Catch up quick: COVID-19</title>
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    display: block;
  }
}


@media screen and (max-width: 650px) {
  .post-ufi.single-full-width-button .post-ufi-button-wrapper {
    width: 100%;
    padding: 16px;
  }
  .post-ufi.single-full-width-button .post-ufi-button-wrapper:empty {
    display: none;
  }
  .post-ufi.single-full-width-button .post-ufi-button {
    width: 100%;
    justify-content: center;
  }
}


@media screen and (max-width: 768px) {
  .file-embed-wrapper {
    padding: 0;
  }
}


@media screen and (max-width: 768px) {
  .file-embed-wrapper-editor {
    padding: 0;
  }
}


@media screen and (max-width: 768px) {
  .file-embed-wrapper-editor:active {
    padding: 0;
  }
}


@media only screen and (max-width: 650px) {
  .file-embed-button.wide,
  .file-embed-error-button.wide {
    display: none;
  }
}


@media only screen and (min-width: 630px) {
  .file-embed-button.narrow,
  .file-embed-error-button.narrow {
    display: none;
  }
}


@media screen and (min-width: 541px) {
  .audio-player-wrapper .audio-player {
    min-width: 500px;
  }
}


@media screen and (max-width: 650px) {
  .audio-player-wrapper .audio-player .audio-player-progress {
    border-left-width: 16px;
    border-right-width: 16px;
  }
}


@media screen and (max-width: 650px) {
  .audio-player-wrapper .audio-player .audio-player-progress .audio-player-progress-bar .audio-player-progress-bar-popup {
    top: -54px;
  }
}


@media screen and (max-width: 650px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-progress {
    border-left-width: 16px;
    border-right-width: 16px;
  }
}


@media screen and (max-width: 650px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-progress .audio-player-progress-bar .audio-player-progress-bar-popup {
    top: -54px;
  }
}


@media (min-width: 250px) {
  .audio-player-wrapper-fancy .audio-player {
    padding: 32px;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group {
    display: flex;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group .button:last-of-type {
    display: block;
  }
}


@media (min-width: 300px) {
  .audio-player-wrapper-fancy .audio-player .btn-group {
    display: block;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group .button:first-of-type {
    display: block;
  }
}


@media (min-width: 350px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-substack-logo {
    display: block;
  }
  .audio-player-wrapper-fancy .audio-player .audio-player-title {
    margin-top: 16px;
  }
  .audio-player-wrapper-fancy .audio-player .audio-player-hero-image-container {
    padding-top: 15%;
    width: 15%;
    display: block;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group .button:first-of-type {
    display: block;
  }
  .audio-player-wrapper-fancy .audio-player .audio-player-substack-logo {
    display: block;
  }
}


@media (min-width: 350px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-hero-image-container {
    padding-top: 25%;
    width: 25%;
    display: block;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group {
    display: flex;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group .button:first-of-type {
    display: block;
  }
}


@media (min-width: 400px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-hero-image-container {
    padding-top: 40%;
    width: 40%;
  }
}


@media (max-width: 400px) {
  .audio-player-wrapper-fancy .audio-player .btn-group {
    margin-top: 12px;
  }
  .audio-player-wrapper-fancy .audio-player .btn-group .button {
    font-size: 13px;
    padding: 6px 12px;
    height: auto;
    margin-top: 10px;
  }
}


@media (min-width: 600px) {
  .audio-player-wrapper-fancy .audio-player .audio-player-hero-image-container {
    padding-top: 55%;
    width: 55%;
  }
}


@media (max-width: 650px) {
  .poll-editor-modal {
    min-width: calc(100% - 20px);
  }
}


@media (max-width: 750px) {
  .poll-embed .poll-anchor-target .poll-anchor-copy-button {
    left: 8px;
    top: 45px;
  }
}


@media screen and (min-width: 541px) {
  .poll-embed .poll-wrapper.poll-web .poll-dialog .modal-table .modal-row .modal-content > .container {
    width: 552px;
    padding: 26px 24px;
  }
}


@media screen and (max-width: 650px) {
  .poll-embed .poll-wrapper.poll-web .poll-dialog .modal-table .modal-row .modal-content > .container {
    padding: 40px 0;
  }
}


@media screen and (max-width: 650px) {
  .poll-embed .poll-wrapper.poll-web .poll-dialog .modal-row .modal-cell .modal-exit-btn {
    margin-right: -20px;
  }
}


@media not all and (min-resolution: 0.001dpcm) {
}
</style><img
src="https://mailgun.substack.com/api/v1/email/open?token=eyJtIjoiPDIwMjMwNTI1MTExNTA3LjMuMzAzOGZiOTI2ZjlkZGRmZEBtZy1kMS5zdWJzdGFjay5jb20-IiwidSI6NDY3OTkzLCJyIjoibWFubnlAcmF0YWZpYXMuY29tIiwiZCI6Im1nLWQxLnN1YnN0YWNrLmNvbSIsInAiOjEyMzE1ODc3MiwidCI6Im5ld3NsZXR0ZXIiLCJhIjoiZXZlcnlvbmUiLCJzIjoyODEyMTksImMiOiJwb3N0IiwiZiI6dHJ1ZSwicG9zaXRpb24iOiJ0b3AiLCJpYXQiOjE2ODUwMTM0NzAsImV4cCI6MTY4NzYwNTQ3MCwiaXNzIjoicHViLTAiLCJzdWIiOiJlbyJ9.iARpIyI2NMSvNse35DWl5TEaARDqEQGDhUl6jMY09Yg"
          alt="" style="height:1px !important;width:1px
          !important;border-width:0 !important;margin-top:0
          !important;margin-bottom:0 !important;margin-right:0
          !important;margin-left:0 !important;padding-top:0
          !important;padding-bottom:0 !important;padding-right:0
          !important;padding-left:0 !important;" moz-do-not-send="true"
          width="1" height="1" border="0"><img
src="https://eotrx.substackcdn.com/open?token=eyJtIjoiPDIwMjMwNTI1MTExNTA3LjMuMzAzOGZiOTI2ZjlkZGRmZEBtZy1kMS5zdWJzdGFjay5jb20-IiwidSI6NDY3OTkzLCJyIjoibWFubnlAcmF0YWZpYXMuY29tIiwiZCI6Im1nLWQxLnN1YnN0YWNrLmNvbSIsInAiOjEyMzE1ODc3MiwidCI6Im5ld3NsZXR0ZXIiLCJhIjoiZXZlcnlvbmUiLCJzIjoyODEyMTksImMiOiJwb3N0IiwiZiI6dHJ1ZSwicG9zaXRpb24iOiJ0b3AiLCJpYXQiOjE2ODUwMTM0NzAsImV4cCI6MTY4NzYwNTQ3MCwiaXNzIjoicHViLTAiLCJzdWIiOiJlbyJ9.iARpIyI2NMSvNse35DWl5TEaARDqEQGDhUl6jMY09Yg"
          alt="" style="height:1px !important;width:1px
          !important;border-width:0 !important;margin-top:0
          !important;margin-bottom:0 !important;margin-right:0
          !important;margin-left:0 !important;padding-top:0
          !important;padding-bottom:0 !important;padding-right:0
          !important;padding-left:0 !important;" moz-do-not-send="true"
          width="1" height="1" border="0">
        <div
style="display:none;font-size:1px;color:#333333;line-height:1px;max-height:0px;max-width:0px;opacity:0;overflow:hidden;"
          class="preview">We survived the end of the public health
          emergency. Here’s the state of affairs. Surveillance
          SARS-CoV-2 is nosediving across all metrics in all regions of
          the U.S.: hospitalizations, deaths, emergency room
          departments, and wastewater. Wastewater is still higher than
          in 2020 and 2021, though.
 ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌ ‌</div>
        <table role="presentation" class="email-body-container"
          width="100%" cellspacing="0" cellpadding="0" border="0">
          <tbody>
            <tr>
              <td><br>
              </td>
              <td class="content" width="550"><br>
              </td>
              <td><br>
              </td>
            </tr>
            <tr>
              <td><br>
              </td>
              <td class="content" width="550" align="left">
                <div style="font-size: 16px; line-height: 26px; margin:
                  0 auto; max-width: 550px; overflow-wrap: break-word;
                  width: 100%;">
                  <table role="presentation" width="100%"
                    cellspacing="0" cellpadding="0" border="0">
                    <tbody>
                      <tr>
                        <td style="height: 20px;" align="right">
                          <table role="presentation" width="auto"
                            cellspacing="0" cellpadding="0" border="0">
                            <tbody>
                              <tr>
                                <td style="vertical-align: middle;"><span
                                    class="tw-font-body tw-text-ssm
                                    tw-text-substack-secondary"
                                    style="color: #808080 !important;
                                    font-family: SF Pro Text,
                                    -apple-system, BlinkMacSystemFont,
                                    Inter, Segoe UI, Roboto, Helvetica,
                                    Arial, sans-serif, Apple Color
                                    Emoji, Segoe UI Emoji, Segoe UI
                                    Symbol !important; font-size: 13px
                                    !important;"><a
href="https://open.substack.com/pub/yourlocalepidemiologist/p/catch-up-quick-covid-19-d2b?utm_source=email&redirect=app-store"
                                      class="tw-text-substack-secondary
                                      tw-underline"
                                      style="-webkit-text-decoration-line:
                                      underline !important; color:
                                      #808080 !important;
                                      text-decoration-line: underline
                                      !important;"
                                      moz-do-not-send="true">Open in app</a>
                                    or <a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly95b3VybG9jYWxlcGlkZW1pb2xvZ2lzdC5zdWJzdGFjay5jb20vcC9jYXRjaC11cC1xdWljay1jb3ZpZC0xOS1kMmI_dG9rZW49ZXlKMWMyVnlYMmxrSWpvME5qYzVPVE1zSW5CdmMzUmZhV1FpT2pFeU16RTFPRGMzTWl3aWFXRjBJam94TmpnMU1ERXpORFk1TENKbGVIQWlPakUyT0RjMk1EVTBOamtzSW1semN5STZJbkIxWWkweU9ERXlNVGtpTENKemRXSWlPaUp3YjNOMExYSmxZV04wYVc5dUluMC5LVWhnWEd5TFZWdXcxYUpMLTNITk1zeFFjWFFCXy0zVkV3M0U2NWMyOGVrIiwicCI6MTIzMTU4NzcyLCJzIjoyODEyMTksImYiOnRydWUsInUiOjQ2Nzk5MywiaWF0IjoxNjg1MDEzNDY5LCJleHAiOjE2ODc2MDU0NjksImlzcyI6InB1Yi0wIiwic3ViIjoibGluay1yZWRpcmVjdCJ9.oFaeqWGNTeuTEOJrAMUD6Qfi17mpc0WY4Fn8s0d3_iM?"
                                      class="tw-text-substack-secondary
                                      tw-underline"
                                      style="-webkit-text-decoration-line:
                                      underline !important; color:
                                      #808080 !important;
                                      text-decoration-line: underline
                                      !important;"
                                      moz-do-not-send="true">online</a></span></td>
                              </tr>
                            </tbody>
                          </table>
                        </td>
                      </tr>
                    </tbody>
                  </table>
                  <table role="presentation" class="header
                    graphic-header" style="border-spacing: 0; padding:
                    16px 0 32px;" width="auto">
                    <tbody>
                      <tr>
                        <td style="padding: 0; text-align: center;"
                          align="center"><a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly95b3VybG9jYWxlcGlkZW1pb2xvZ2lzdC5zdWJzdGFjay5jb20vcC9jYXRjaC11cC1xdWljay1jb3ZpZC0xOS1kMmI_dG9rZW49ZXlKMWMyVnlYMmxrSWpvME5qYzVPVE1zSW5CdmMzUmZhV1FpT2pFeU16RTFPRGMzTWl3aWFXRjBJam94TmpnMU1ERXpORFk1TENKbGVIQWlPakUyT0RjMk1EVTBOamtzSW1semN5STZJbkIxWWkweU9ERXlNVGtpTENKemRXSWlPaUp3YjNOMExYSmxZV04wYVc5dUluMC5LVWhnWEd5TFZWdXcxYUpMLTNITk1zeFFjWFFCXy0zVkV3M0U2NWMyOGVrIiwicCI6MTIzMTU4NzcyLCJzIjoyODEyMTksImYiOnRydWUsInUiOjQ2Nzk5MywiaWF0IjoxNjg1MDEzNDY5LCJleHAiOjE2ODc2MDU0NjksImlzcyI6InB1Yi0wIiwic3ViIjoibGluay1yZWRpcmVjdCJ9.oFaeqWGNTeuTEOJrAMUD6Qfi17mpc0WY4Fn8s0d3_iM?"
                            moz-do-not-send="true"><img
                              role="presentation"
src="https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fbucketeer-e05bbc84-baa3-437e-9518-adb32be77984.s3.amazonaws.com%2Fpublic%2Fimages%2F523ac601-a63a-4d07-906e-bc4e7bfbb83a_2200x440.png"
                              class="header-image" style="border: none
                              !important; display: block; height: auto;
                              margin: 0 auto; max-width: 550px;
                              vertical-align: middle; width: 100%;"
                              moz-do-not-send="true" width="550"
                              height="110"></a></td>
                      </tr>
                    </tbody>
                  </table>
                  <div class="typography" style="font-size: 16px;
                    line-height: 26px;">
                    <div class="preamble" style="font-size: 16px;
                      line-height: 26px; margin-top: 16px;">
                      <div dir="auto" class="body markup"
                        style="font-size: 16px; line-height: 26px;
                        margin-bottom: 16px; text-align: initial; width:
                        100%; word-break: break-word;">
                        <p style="color: #404040; font-size: 16px;
                          line-height: 26px; margin: 0 0 20px 0;
                          margin-bottom: 0; margin-top: 0;"><em><span>Si
                              quiere leer la versión en español, pulse </span><a
href="https://substack.com/redirect/ce461f72-e00f-42d1-89fc-31c75e793cdf?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">aquí</a><span>.</span></em></p>
                      </div>
                      <hr style="background: #e0e0e0; border: none;
                        height: 1px; margin: 16px 0 0; padding: 0;"></div>
                  </div>
                  <div dir="auto" class="post typography"
                    style="font-size: 16px; line-height: 26px; padding:
                    16px 0 0 0;">
                    <div class="post-header" style="font-size: 16px;
                      line-height: 26px;">
                      <h1 class="post-title published"
                        style="-moz-appearance: optimizelegibility;
                        -moz-osx-font-smoothing: antialiased;
                        -webkit-appearance: optimizelegibility;
                        -webkit-font-smoothing: antialiased; appearance:
                        optimizelegibility; color: #404040; font-family:
                        'SF Pro Display', -apple-system,
                        BlinkMacSystemFont, 'Inter', 'Segoe UI', Roboto,
                        Helvetica, Arial, sans-serif, 'Apple Color
                        Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';
                        font-size: 32px; font-weight: 900; line-height:
                        36px; margin: 0;"><a
href="https://substack.com/app-link/post?publication_id=281219&post_id=123158772&utm_source=post-email-title&isFreemail=true&token=eyJ1c2VyX2lkIjo0Njc5OTMsInBvc3RfaWQiOjEyMzE1ODc3MiwiaWF0IjoxNjg1MDEzNDY5LCJleHAiOjE2ODc2MDU0NjksImlzcyI6InB1Yi0yODEyMTkiLCJzdWIiOiJwb3N0LXJlYWN0aW9uIn0.KUhgXGyLVVuw1aJL-3HNMsxQcXQB_-3VEw3E65c28ek"
                          style="color: #404040; text-decoration: none;"
                          moz-do-not-send="true">Catch up quick:
                          COVID-19</a></h1>
                      <table role="presentation" class="post-meta"
                        style="align-items: center; height: 20px;
                        margin: 1em 0;" width="100%" cellspacing="0"
                        cellpadding="0" border="0">
                        <tbody>
                          <tr>
                            <td>
                              <table role="presentation" width="auto"
                                cellspacing="0" cellpadding="0"
                                border="0">
                                <tbody>
                                  <tr>
                                    <td>
                                      <table role="presentation"
                                        width="auto" cellspacing="0"
                                        cellpadding="0" border="0">
                                        <tbody>
                                          <tr>
                                            <td style="vertical-align:
                                              middle;">
                                              <div class="pencraft
                                                frontend-pencraft-Box-module__reset--tAIEo
frontend-pencraft-Text-module__size-11--1-ofT
                                                frontend-pencraft-Text-module__line-height-20--1soeQ
frontend-pencraft-Text-module__weight-medium--aTbx5
                                                frontend-pencraft-Text-module__font-meta--2i-cR
frontend-pencraft-Text-module__color-primary--2I-sF
                                                frontend-pencraft-Text-module__transform-uppercase--38jbr
frontend-pencraft-Text-module__reset--20JLV
                                                frontend-pencraft-Text-module__meta--3RRSj
custom-css-email-post-author" style="color: #404040; font-family: 'SF
                                                Compact', -apple-system,
                                                -apple-system,
                                                -system-ui,
                                                BlinkMacSystemFont,
                                                'Segoe UI', Roboto,
                                                Helvetica, Arial,
                                                sans-serif, 'Apple Color
                                                Emoji', 'Segoe UI
                                                Emoji', 'Segoe UI
                                                Symbol'; font-size:
                                                11px; font-weight: 500;
                                                letter-spacing: .2px;
                                                line-height: 20px;
                                                margin: 0;
                                                text-decoration: unset;
                                                text-transform:
                                                uppercase;"><a
                                                  style="color: #404040;
                                                  font-family: 'SF
                                                  Compact',
                                                  -apple-system,
                                                  -apple-system,
                                                  -system-ui,
                                                  BlinkMacSystemFont,
                                                  'Segoe UI', Roboto,
                                                  Helvetica, Arial,
                                                  sans-serif, 'Apple
                                                  Color Emoji', 'Segoe
                                                  UI Emoji', 'Segoe UI
                                                  Symbol'; font-size:
                                                  11px; font-weight:
                                                  500; letter-spacing:
                                                  .2px; line-height:
                                                  20px; margin: 0;
                                                  text-decoration: none;
                                                  text-transform:
                                                  uppercase;"
href="https://substack.com/redirect/351f4f40-78b6-4cd4-9628-48b70b6c5468?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                                  class="pencraft
                                                  frontend-pencraft-Box-module__reset--tAIEo
frontend-pencraft-Text-module__size-11--1-ofT
                                                  frontend-pencraft-Text-module__line-height-20--1soeQ
frontend-pencraft-Text-module__weight-medium--aTbx5
                                                  frontend-pencraft-Text-module__font-meta--2i-cR
frontend-pencraft-Text-module__color-primary--2I-sF
                                                  frontend-pencraft-Text-module__transform-uppercase--38jbr
frontend-pencraft-Text-module__reset--20JLV
                                                  frontend-pencraft-Text-module__meta--3RRSj"
                                                  moz-do-not-send="true">Katelyn
                                                  Jetelina</a></div>
                                            </td>
                                          </tr>
                                        </tbody>
                                      </table>
                                    </td>
                                  </tr>
                                  <tr>
                                    <td>
                                      <table role="presentation"
                                        width="auto" cellspacing="0"
                                        cellpadding="0" border="0">
                                        <tbody>
                                          <tr>
                                            <td style="vertical-align:
                                              middle;">
                                              <div class="pencraft
                                                frontend-pencraft-Box-module__reset--tAIEo
frontend-pencraft-Text-module__size-11--1-ofT
                                                frontend-pencraft-Text-module__line-height-20--1soeQ
frontend-pencraft-Text-module__weight-medium--aTbx5
                                                frontend-pencraft-Text-module__font-meta--2i-cR
frontend-pencraft-Text-module__color-secondary--XjVGl
                                                frontend-pencraft-Text-module__transform-uppercase--38jbr
frontend-pencraft-Text-module__reset--20JLV
                                                frontend-pencraft-Text-module__meta--3RRSj"
                                                style="color: #808080;
                                                font-family: 'SF
                                                Compact', -apple-system,
                                                -apple-system,
                                                -system-ui,
                                                BlinkMacSystemFont,
                                                'Segoe UI', Roboto,
                                                Helvetica, Arial,
                                                sans-serif, 'Apple Color
                                                Emoji', 'Segoe UI
                                                Emoji', 'Segoe UI
                                                Symbol'; font-size:
                                                11px; font-weight: 500;
                                                letter-spacing: .2px;
                                                line-height: 20px;
                                                margin: 0;
                                                text-decoration: unset;
                                                text-transform:
                                                uppercase;"><time
                                                  datetime="2023-05-25T11:17:21.250Z">May
                                                  25</time></div>
                                            </td>
                                          </tr>
                                        </tbody>
                                      </table>
                                    </td>
                                  </tr>
                                </tbody>
                              </table>
                            </td>
                            <td align="right">
                              <table role="presentation" width="auto"
                                cellspacing="0" cellpadding="0"
                                border="0">
                                <tbody>
                                  <tr>
                                    <td style="vertical-align: middle;"><a
href="https://substack.com/redirect/351f4f40-78b6-4cd4-9628-48b70b6c5468?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                        moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fbucketeer-e05bbc84-baa3-437e-9518-adb32be77984.s3.amazonaws.com%2Fpublic%2Fimages%2Fb1cf8441-2181-452a-a5af-364eb49b32b5_828x1792.png"
                                          style="border: none
                                          !important; border-radius:
                                          500000px; box-sizing:
                                          border-box; display: inline;
                                          height: 40px; margin: 0px;
                                          max-width: 550px; min-height:
                                          40px; min-width: 40px;
                                          object-fit: cover;
                                          vertical-align: middle; width:
                                          40px;"
                                          class="custom-css-email-avatar
frontend-email-system-basics-module__avatar--1sRIo"
                                          moz-do-not-send="true"
                                          width="40" height="40"></a></td>
                                  </tr>
                                </tbody>
                              </table>
                            </td>
                          </tr>
                        </tbody>
                      </table>
                      <table role="presentation" class="email-ufi-2-top"
                        style="border-bottom: 1px solid rgba(0, 0, 0,
                        .13); border-top: 1px solid rgba(0, 0, 0, .13);
                        min-width: 100%;" width="100%" cellspacing="0"
                        cellpadding="0" border="0">
                        <tbody>
                          <tr height="16">
                            <td style="font-size: 0px; line-height: 0;"
                              height="16"> </td>
                          </tr>
                          <tr>
                            <td>
                              <table role="presentation" width="100%"
                                cellspacing="0" cellpadding="0"
                                border="0">
                                <tbody>
                                  <tr>
                                    <td>
                                      <table role="presentation"
                                        width="auto" cellspacing="0"
                                        cellpadding="0" border="0">
                                        <tbody>
                                          <tr>
                                            <td style="vertical-align:
                                              middle;">
                                              <table role="presentation"
                                                width="38"
                                                cellspacing="0"
                                                cellpadding="0"
                                                border="0">
                                                <tbody>
                                                  <tr>
                                                    <td align="center"><a
href="https://substack.com/app-link/post?publication_id=281219&post_id=123158772&utm_source=substack&isFreemail=true&submitLike=true&token=eyJ1c2VyX2lkIjo0Njc5OTMsInBvc3RfaWQiOjEyMzE1ODc3MiwicmVhY3Rpb24iOiLinaQiLCJpYXQiOjE2ODUwMTM0NjksImV4cCI6MTY4NzYwNTQ2OSwiaXNzIjoicHViLTI4MTIxOSIsInN1YiI6InJlYWN0aW9uIn0.Sj4DdlcfIj_R2or6GpGOqjKTdReAel9FXSfvQIzXESw&utm_medium=email"
                                                        style="border:
                                                        1px solid
                                                        rgba(0, 0, 0,
                                                        .13);
                                                        border-radius:
                                                        100000px;
                                                        box-sizing:
                                                        border-box;
                                                        color: #808080;
                                                        display:
                                                        inline-block;
                                                        font-family: 'SF
                                                        Pro Text',
                                                        -apple-system,
                                                        ui-sans-serif,
                                                        BlinkMacSystemFont,
                                                        'Segoe UI',
                                                        Roboto,
                                                        Helvetica,
                                                        Arial,
                                                        sans-serif,
                                                        'Apple Color
                                                        Emoji', 'Segoe
                                                        UI Emoji',
                                                        'Segoe UI
                                                        Symbol';
                                                        font-size: 12px;
                                                        font-weight:
                                                        500;
                                                        line-height: 1;
                                                        min-width: 38px;
                                                        padding: 9px 0;
                                                        text-decoration:
                                                        none;
                                                        text-transform:
                                                        uppercase;
                                                        width: 38px;"
                                                        class="email-icon-button"
moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Ficon%2FLucideHeart%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2"
                                                          style="border:
                                                          none
                                                          !important;
                                                          max-width:
                                                          18px;
                                                          vertical-align:
                                                          middle;"
                                                          alt=""
                                                          class="icon"
                                                          moz-do-not-send="true"
                                                          width="18"
                                                          height="18"></a></td>
                                                  </tr>
                                                </tbody>
                                              </table>
                                            </td>
                                            <td style="min-width: 8px"
                                              width="8"><br>
                                            </td>
                                            <td style="vertical-align:
                                              middle;">
                                              <table role="presentation"
                                                width="38"
                                                cellspacing="0"
                                                cellpadding="0"
                                                border="0">
                                                <tbody>
                                                  <tr>
                                                    <td align="center"><a
href="https://substack.com/app-link/post?publication_id=281219&post_id=123158772&utm_source=substack&utm_medium=email&isFreemail=true&comments=true&token=eyJ1c2VyX2lkIjo0Njc5OTMsInBvc3RfaWQiOjEyMzE1ODc3MiwiaWF0IjoxNjg1MDEzNDY5LCJleHAiOjE2ODc2MDU0NjksImlzcyI6InB1Yi0yODEyMTkiLCJzdWIiOiJwb3N0LXJlYWN0aW9uIn0.KUhgXGyLVVuw1aJL-3HNMsxQcXQB_-3VEw3E65c28ek&utm_source=substack&utm_medium=email"
                                                        style="border:
                                                        1px solid
                                                        rgba(0, 0, 0,
                                                        .13);
                                                        border-radius:
                                                        100000px;
                                                        box-sizing:
                                                        border-box;
                                                        color: #808080;
                                                        display:
                                                        inline-block;
                                                        font-family: 'SF
                                                        Pro Text',
                                                        -apple-system,
                                                        ui-sans-serif,
                                                        BlinkMacSystemFont,
                                                        'Segoe UI',
                                                        Roboto,
                                                        Helvetica,
                                                        Arial,
                                                        sans-serif,
                                                        'Apple Color
                                                        Emoji', 'Segoe
                                                        UI Emoji',
                                                        'Segoe UI
                                                        Symbol';
                                                        font-size: 12px;
                                                        font-weight:
                                                        500;
                                                        line-height: 1;
                                                        min-width: 38px;
                                                        padding: 9px 0;
                                                        text-decoration:
                                                        none;
                                                        text-transform:
                                                        uppercase;
                                                        width: 38px;"
                                                        class="email-icon-button"
moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Ficon%2FLucideComments%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2"
                                                          style="border:
                                                          none
                                                          !important;
                                                          max-width:
                                                          18px;
                                                          vertical-align:
                                                          middle;"
                                                          alt=""
                                                          class="icon"
                                                          moz-do-not-send="true"
                                                          width="18"
                                                          height="18"></a></td>
                                                  </tr>
                                                </tbody>
                                              </table>
                                            </td>
                                            <td style="min-width: 8px"
                                              width="8"><br>
                                            </td>
                                            <td style="vertical-align:
                                              middle;">
                                              <table role="presentation"
                                                width="38"
                                                cellspacing="0"
                                                cellpadding="0"
                                                border="0">
                                                <tbody>
                                                  <tr>
                                                    <td align="center"><a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly95b3VybG9jYWxlcGlkZW1pb2xvZ2lzdC5zdWJzdGFjay5jb20vcC9jYXRjaC11cC1xdWljay1jb3ZpZC0xOS1kMmI_dXRtX3NvdXJjZT1zdWJzdGFjayZ1dG1fbWVkaXVtPWVtYWlsJmFjdGlvbj1yZXN0YWNrLWNvbW1lbnQiLCJwIjoxMjMxNTg3NzIsInMiOjI4MTIxOSwiZiI6dHJ1ZSwidSI6NDY3OTkzLCJpYXQiOjE2ODUwMTM0NjksImV4cCI6MTY4NzYwNTQ2OSwiaXNzIjoicHViLTAiLCJzdWIiOiJsaW5rLXJlZGlyZWN0In0.t4_G6-Ge-PzIdmtCB-GV2gqsWudUgEAfBu100uLxp9E?&utm_source=substack&utm_medium=email"
                                                        style="border:
                                                        1px solid
                                                        rgba(0, 0, 0,
                                                        .13);
                                                        border-radius:
                                                        100000px;
                                                        box-sizing:
                                                        border-box;
                                                        color: #808080;
                                                        display:
                                                        inline-block;
                                                        font-family: 'SF
                                                        Pro Text',
                                                        -apple-system,
                                                        ui-sans-serif,
                                                        BlinkMacSystemFont,
                                                        'Segoe UI',
                                                        Roboto,
                                                        Helvetica,
                                                        Arial,
                                                        sans-serif,
                                                        'Apple Color
                                                        Emoji', 'Segoe
                                                        UI Emoji',
                                                        'Segoe UI
                                                        Symbol';
                                                        font-size: 12px;
                                                        font-weight:
                                                        500;
                                                        line-height: 1;
                                                        min-width: 38px;
                                                        padding: 9px 0;
                                                        text-decoration:
                                                        none;
                                                        text-transform:
                                                        uppercase;
                                                        width: 38px;"
                                                        class="email-icon-button"
moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Ficon%2FNoteForwardIcon%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2"
                                                          style="border:
                                                          none
                                                          !important;
                                                          max-width:
                                                          18px;
                                                          vertical-align:
                                                          middle;"
                                                          alt=""
                                                          class="icon"
                                                          moz-do-not-send="true"
                                                          width="18"
                                                          height="18"></a></td>
                                                  </tr>
                                                </tbody>
                                              </table>
                                            </td>
                                          </tr>
                                        </tbody>
                                      </table>
                                    </td>
                                    <td align="right">
                                      <table role="presentation"
                                        width="auto" cellspacing="0"
                                        cellpadding="0" border="0">
                                        <tbody>
                                          <tr>
                                            <td style="vertical-align:
                                              middle;">
                                              <table role="presentation"
                                                width="auto"
                                                cellspacing="0"
                                                cellpadding="0"
                                                border="0">
                                                <tbody>
                                                  <tr>
                                                    <td align="center"><a
href="https://substack.com/app-link/post?publication_id=281219&post_id=123158772&utm_source=substack&utm_medium=email&utm_content=share&action=share&triggerShare=true&isFreemail=true&token=eyJ1c2VyX2lkIjo0Njc5OTMsInBvc3RfaWQiOjEyMzE1ODc3MiwiaWF0IjoxNjg1MDEzNDY5LCJleHAiOjE2ODc2MDU0NjksImlzcyI6InB1Yi0yODEyMTkiLCJzdWIiOiJwb3N0LXJlYWN0aW9uIn0.KUhgXGyLVVuw1aJL-3HNMsxQcXQB_-3VEw3E65c28ek"
class="email-button-outline" style="border: 1px solid rgba(0, 0, 0,
                                                        .13);
                                                        border-radius:
                                                        100000px; color:
                                                        #808080;
                                                        display:
                                                        inline-block;
                                                        font-family: 'SF
                                                        Pro Text',
                                                        -apple-system,
                                                        ui-sans-serif,
                                                        BlinkMacSystemFont,
                                                        'Segoe UI',
                                                        Roboto,
                                                        Helvetica,
                                                        Arial,
                                                        sans-serif,
                                                        'Apple Color
                                                        Emoji', 'Segoe
                                                        UI Emoji',
                                                        'Segoe UI
                                                        Symbol';
                                                        font-size: 12px;
                                                        font-weight:
                                                        500;
                                                        line-height:
                                                        12px; padding:
                                                        9px 14px;
                                                        text-decoration:
                                                        none;
                                                        text-transform:
                                                        uppercase;"
                                                        moz-do-not-send="true"><span
class="email-button-text" style="vertical-align: middle;">Share</span></a></td>
                                                  </tr>
                                                </tbody>
                                              </table>
                                            </td>
                                          </tr>
                                        </tbody>
                                      </table>
                                    </td>
                                  </tr>
                                </tbody>
                              </table>
                            </td>
                          </tr>
                          <tr height="16">
                            <td style="font-size: 0px; line-height: 0;"
                              height="16"> </td>
                          </tr>
                        </tbody>
                      </table>
                    </div>
                  </div>
                  <div dir="auto" class="post typography"
                    style="font-size: 16px; line-height: 26px; padding:
                    16px 0 0 0;">
                    <div dir="auto" class="body markup"
                      style="font-size: 16px; line-height: 26px;
                      margin-bottom: 16px; text-align: initial; width:
                      100%; word-break: break-word;">
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;
                        margin-top: 0;">We survived the end of the
                        public health emergency. Here’s the state of
                        affairs.</p>
                      <h4 class="header-with-anchor-widget"
                        style="-moz-appearance: optimizelegibility;
                        -moz-osx-font-smoothing: antialiased;
                        -webkit-appearance: optimizelegibility;
                        -webkit-font-smoothing: antialiased; appearance:
                        optimizelegibility; color: #404040; font-family:
                        'SF Compact Display', -apple-system,
                        BlinkMacSystemFont, 'Segoe UI', Roboto,
                        Helvetica, Arial, sans-serif, 'Apple Color
                        Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';
                        font-size: 1.125em; font-weight: bold;
                        line-height: 1.16em; margin: 1em 0 0.625em 0;
                        position: relative;">Surveillance</h4>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;">SARS-CoV-2
                        is nosediving across all metrics in all regions
                        of the U.S.: hospitalizations, deaths, emergency
                        room departments, and wastewater. Wastewater is
                        still higher than in 2020 and 2021, though. </p>
                      <div class="captioned-image-container-static"
                        style="font-size: 16px; line-height: 26px;
                        margin: 32px auto;">
                        <figure style="margin: 0 auto; width: 100%;">
                          <table class="image-wrapper"
                            data-component-name="Image2ToDOMStatic"
                            style="mso-padding-alt: 1em 0 1.6em;"
                            width="100%" cellspacing="0" cellpadding="0"
                            border="0">
                            <tbody>
                              <tr>
                                <td style="text-align: center;"><br>
                                </td>
                                <td class="content" style="text-align:
                                  center;" width="1456" align="left"><a
                                    class="image-link" target="_blank"
href="https://substack.com/redirect/d60c209f-b3e4-4823-955e-782411529df0?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                    rel="" style="align-items: center;
                                    border: none; display: block;
                                    flex-direction: column; height:
                                    auto; margin: 0; padding: 0;
                                    position: relative; text-decoration:
                                    none; width: auto;"
                                    moz-do-not-send="true"><img
data-attrs="{"src":"https://substack-post-media.s3.amazonaws.com/public/images/52292cc9-5a83-4735-92e5-bd464331d135_2420x1195.jpeg","fullscreen":null,"imageSize":null,"height":719,"width":1456,"resizeWidth":null,"bytes":198457,"alt":null,"title":null,"type":"image/jpeg","href":null,"belowTheFold":false,"topImage":true,"internalRedirect":null}"
                                      alt="" class="wide-image"
src="https://substackcdn.com/image/fetch/w_2912,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F52292cc9-5a83-4735-92e5-bd464331d135_2420x1195.jpeg"
                                      style="-ms-interpolation-mode:
                                      bicubic; border: none !important;
                                      display: block; height: auto;
                                      margin: 0 auto; margin-bottom: 0;
                                      max-width: 100% !important;
                                      vertical-align: middle; width:
                                      auto !important;"
                                      moz-do-not-send="true" width="550"
                                      height="271.60027472527474"></a></td>
                                <td style="text-align: center;"><br>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                        </figure>
                      </div>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;"><span>We’ve
                          been hitting new lows in death counts, too. In
                          fact, excess deaths are hovering at only </span><a
href="https://substack.com/redirect/9250ba62-69ce-4936-8c02-768c3405b4fa?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                          rel="" style="color: #538cfa; text-decoration:
                          none;" moz-do-not-send="true">~1%</a><span>
                          above pre-pandemic rates (at the height of the
                          pandemic we were at 47%). In other words,
                          things are looking good right now. </span></p>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;"><span>It
                          will be interesting to watch what happens this
                          summer, as the South has consistently faced a
                          COVID-19 wave. </span><a
href="https://substack.com/redirect/a22f0972-4e15-4581-a6f0-50ff3111c3d9?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                          rel="" style="color: #538cfa; text-decoration:
                          none;" moz-do-not-send="true">Most scientists
                        </a><span>(including me) are betting that we
                          will continue to see </span><em>wavelets</em><span>,
                          at least until winter.</span></p>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;"><span>Virologists
                          continue to identify “cryptic lineages” in
                          wastewater, though. These are highly mutated
                          COVID-19 variants that randomly pop up on our
                          radar. The latest (right below) was detected
                          ~12 hours ago. None have taken off yet, but
                          are a lingering reminder that a variant of
                          concern could be brewing in the background. We
                          still have many </span><a
href="https://substack.com/redirect/eae0f574-c355-4f9d-8796-22ffd0e3da58?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                          rel="" style="color: #538cfa; text-decoration:
                          none;" moz-do-not-send="true">unanswered
                          questions</a><span> about cryptic lineages: </span><em>What
                          is the health status of the person?</em><span>
                        </span><em>Do they have long COVID? Where in the
                          body is the virus replicating? </em></p>
                      <div class="captioned-image-container-static"
                        style="font-size: 16px; line-height: 26px;
                        margin: 32px auto;">
                        <figure style="margin: 0 auto; width: 100%;">
                          <table class="image-wrapper"
                            data-component-name="Image2ToDOMStatic"
                            style="mso-padding-alt: 1em 0 1.6em;"
                            width="100%" cellspacing="0" cellpadding="0"
                            border="0">
                            <tbody>
                              <tr>
                                <td style="text-align: center;"><br>
                                </td>
                                <td class="content" style="text-align:
                                  center;" width="518" align="left"><a
                                    class="image-link" target="_blank"
href="https://substack.com/redirect/1330a390-2415-48e6-9a3b-1a7bf854b70b?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                    rel="" style="align-items: center;
                                    border: none; display: block;
                                    flex-direction: column; height:
                                    auto; margin: 0; padding: 0;
                                    position: relative; text-decoration:
                                    none; width: auto;"
                                    moz-do-not-send="true"><img
data-attrs="{"src":"https://substack-post-media.s3.amazonaws.com/public/images/f6fc7550-5751-4220-8c2c-87678c9066d3_2182x1020.jpeg","fullscreen":null,"imageSize":null,"height":681,"width":1456,"resizeWidth":518,"bytes":120817,"alt":null,"title":null,"type":"image/jpeg","href":null,"belowTheFold":false,"topImage":false,"internalRedirect":null}"
                                      alt="" class=""
src="https://substackcdn.com/image/fetch/w_518,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff6fc7550-5751-4220-8c2c-87678c9066d3_2182x1020.jpeg"
                                      style="-ms-interpolation-mode:
                                      bicubic; border: none !important;
                                      display: block; height: auto;
                                      margin: 0 auto; margin-bottom: 0;
                                      max-width: 100% !important;
                                      vertical-align: middle; width:
                                      auto !important;"
                                      moz-do-not-send="true" width="518"
                                      height="242.27884615384616"></a></td>
                                <td style="text-align: center;"><br>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                          <figcaption class="image-caption"
                            style="box-sizing: content-box; color:
                            #808080; font-size: 14px; font-weight: 400;
                            letter-spacing: -.15px; line-height: 20px;
                            margin-top: 8px; padding-left: 15%;
                            padding-right: 15%; text-align: center;
                            width: 70%;"><span>SARS-CoV-2 cryptic
                              lineage examples from Marc Johnson </span><a
href="https://substack.com/redirect/9a80ee52-d50e-4474-b390-98e0482d3aea?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="text-decoration: underline;"
                              moz-do-not-send="true">@SolidEvidence</a></figcaption></figure>
                      </div>
                      <h4 class="header-with-anchor-widget"
                        style="-moz-appearance: optimizelegibility;
                        -moz-osx-font-smoothing: antialiased;
                        -webkit-appearance: optimizelegibility;
                        -webkit-font-smoothing: antialiased; appearance:
                        optimizelegibility; color: #404040; font-family:
                        'SF Compact Display', -apple-system,
                        BlinkMacSystemFont, 'Segoe UI', Roboto,
                        Helvetica, Arial, sans-serif, 'Apple Color
                        Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';
                        font-size: 1.125em; font-weight: bold;
                        line-height: 1.16em; margin: 1em 0 0.625em 0;
                        position: relative;">Noteworthy COVID-19 news</h4>
                      <ul style="margin-top: 0; padding: 0;">
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0 0 20px 0; margin-bottom: 0;
                            padding-left: 4px;"><em><strong>Indoor air
                                quality.</strong></em><span> Up until
                              now, the CDC recommended that we “improve
                              ventilation” to reduce transmission. But </span><em>by
                              how much?</em><span> Well, for the first
                              time, CDC set minimum ventilation targets
                              for indoor spaces: 5 air changes per hour.
                              This may sound like boring news, but it’s
                              huge for public health. Not just for
                              viruses but health overall. While this
                              standard isn’t mandatory, you should
                              follow up with your business, school,
                              place of worship, etc. to ensure it’s
                              being met now.</span></p>
                          <table class="poll-embed poll-email"
                            style="margin: 32px auto; max-width: 600px;"
                            width="100%" cellspacing="16px">
                            <tbody>
                              <tr>
                                <td align="center">
                                  <table role="presentation"
                                    class="poll-email-wrapper"
                                    style="border: 1px solid rgba(0, 0,
                                    0, .13); border-radius: 8px; color:
                                    #404040; font-family: -apple-system,
                                    -system-ui, BlinkMacSystemFont,
                                    'Segoe UI', Roboto, Helvetica,
                                    Arial, sans-serif, 'Apple Color
                                    Emoji', 'Segoe UI Emoji', 'Segoe UI
                                    Symbol'; padding: 16px 16px 8px;
                                    width: 100%;" width="auto"
                                    cellspacing="0" cellpadding="0"
                                    border="0">
                                    <tbody>
                                      <tr>
                                        <td>
                                          <table role="presentation"
                                            width="100%" cellspacing="0"
                                            cellpadding="0" border="0">
                                            <tbody>
                                              <tr>
                                                <td class="poll-header"
                                                  style="color: #808080;
                                                  font-size: 12px;
                                                  font-weight: 500;
                                                  line-height: 20px;
                                                  margin-bottom: 4px;
                                                  padding: 0;">POLL</td>
                                              </tr>
                                              <tr width="100%"
                                                class="poll-question"
                                                style="color: #404040;
                                                font-family: 'SF Pro
                                                Display',
                                                -apple-system-headline,
                                                -apple-system,
                                                -system-ui,
                                                BlinkMacSystemFont,
                                                'Segoe UI', Roboto,
                                                Helvetica, Arial,
                                                sans-serif, 'Apple Color
                                                Emoji', 'Segoe UI
                                                Emoji', 'Segoe UI
                                                Symbol'; font-size:
                                                20px; font-weight: 700;
                                                line-height: 32px;
                                                margin-bottom: 8px;
                                                vertical-align: top;">
                                                <td>Are you interested
                                                  in a deeper YLE dive
                                                  into this ventilation
                                                  standard topic? </td>
                                              </tr>
                                              <tr>
                                                <td>
                                                  <table
                                                    role="presentation"
                                                    class="poll-options"
style="border-spacing: 0 12px;" width="100%" cellspacing="0"
                                                    cellpadding="0"
                                                    border="0">
                                                    <tbody>
                                                      <tr>
                                                        <td
                                                          class="poll-option"
                                                          width="100%"><a
href="https://substack.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.z-8bdRmcnKUuijLF1pmeRoHan8zedi8M3M_3XqI9Ojg?"
                                                          width="100%"
                                                          class="poll-vote-link"
style="background-color: #eeeeee; border: 1px solid rgba(0, 0, 0, .13);
                                                          border-radius:
                                                          4px; color:
                                                          #808080;
                                                          display:
                                                          block; height:
                                                          100%; padding:
                                                          10px 0;
                                                          text-align:
                                                          center;
                                                          text-decoration:
                                                          none; width:
                                                          100%;"
                                                          moz-do-not-send="true">
                                                          <div
                                                          class="poll-vote-contents"
                                                          style="color:
                                                          #404040;
                                                          display:
                                                          block;
                                                          font-size:
                                                          14px;
                                                          font-weight:
                                                          600; height:
                                                          100%;
                                                          line-height:
                                                          20px; width:
                                                          100%;">Yes,
                                                          would be super
                                                          helpful</div>
                                                          </a></td>
                                                      </tr>
                                                      <tr>
                                                        <td
                                                          class="poll-option"
                                                          width="100%"><a
href="https://substack.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.CaFZ7r-YBvz6uooZLv03MpJib1ofNya1o2fwvYkuFXk?"
                                                          width="100%"
                                                          class="poll-vote-link"
style="background-color: #eeeeee; border: 1px solid rgba(0, 0, 0, .13);
                                                          border-radius:
                                                          4px; color:
                                                          #808080;
                                                          display:
                                                          block; height:
                                                          100%; padding:
                                                          10px 0;
                                                          text-align:
                                                          center;
                                                          text-decoration:
                                                          none; width:
                                                          100%;"
                                                          moz-do-not-send="true">
                                                          <div
                                                          class="poll-vote-contents"
                                                          style="color:
                                                          #404040;
                                                          display:
                                                          block;
                                                          font-size:
                                                          14px;
                                                          font-weight:
                                                          600; height:
                                                          100%;
                                                          line-height:
                                                          20px; width:
                                                          100%;">Maybe</div>
                                                          </a></td>
                                                      </tr>
                                                      <tr>
                                                        <td
                                                          class="poll-option"
                                                          width="100%"><a
href="https://substack.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.NS4o6PItYHiZQwm9kW2SBQ5IUvoQfTe4t3c79UvUbhg?"
                                                          width="100%"
                                                          class="poll-vote-link"
style="background-color: #eeeeee; border: 1px solid rgba(0, 0, 0, .13);
                                                          border-radius:
                                                          4px; color:
                                                          #808080;
                                                          display:
                                                          block; height:
                                                          100%; padding:
                                                          10px 0;
                                                          text-align:
                                                          center;
                                                          text-decoration:
                                                          none; width:
                                                          100%;"
                                                          moz-do-not-send="true">
                                                          <div
                                                          class="poll-vote-contents"
                                                          style="color:
                                                          #404040;
                                                          display:
                                                          block;
                                                          font-size:
                                                          14px;
                                                          font-weight:
                                                          600; height:
                                                          100%;
                                                          line-height:
                                                          20px; width:
                                                          100%;">Nope,
                                                          I've already
                                                          fallen asleep</div>
                                                          </a></td>
                                                      </tr>
                                                    </tbody>
                                                  </table>
                                                </td>
                                              </tr>
                                            </tbody>
                                          </table>
                                        </td>
                                      </tr>
                                    </tbody>
                                  </table>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                        </li>
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Fall boosters. </strong></em><span>The
                              WHO officially recommends a monovalent
                              (one strain) booster that targets XBB—an
                              Omicron subvariant—this fall. Countries
                              don’t have to follow suit. (The U.S. chose
                              a different vaccine formula than WHO
                              recommended last year, for example.) A big
                              FDA meeting is coming in June to discuss
                              the U.S. plan.</span></p>
                        </li>
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Mask usage</strong></em><span>.
                            </span><a
href="https://substack.com/redirect/c7161890-5ca1-467a-a1c0-cf6511761f89?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">Polling </a><span>on
                              May 6-9 found 46% of respondents wore a
                              mask at least some of the time in the past
                              7 days. Just looking outside, I was
                              surprised about this statistic, but
                              probably because I’m white and in the
                              suburbs, two groups with the lowest rates.
                              We really need to improve masking among
                              older adults, especially in times of high
                              transmission. </span></p>
                        </li>
                      </ul>
                      <div class="captioned-image-container-static"
                        style="font-size: 16px; line-height: 26px;
                        margin: 32px auto;">
                        <figure style="margin: 0 auto; width: 100%;">
                          <table class="image-wrapper"
                            data-component-name="Image2ToDOMStatic"
                            style="mso-padding-alt: 1em 0 1.6em;"
                            width="100%" cellspacing="0" cellpadding="0"
                            border="0">
                            <tbody>
                              <tr>
                                <td style="text-align: center;"><br>
                                </td>
                                <td class="content" style="text-align:
                                  center;" width="478" align="left"><a
                                    class="image-link" target="_blank"
href="https://substack.com/redirect/4309773d-c213-43fc-98ee-1eaf1aa43419?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                    rel="" style="align-items: center;
                                    border: none; display: block;
                                    flex-direction: column; height:
                                    auto; margin: 0; padding: 0;
                                    position: relative; text-decoration:
                                    none; width: auto;"
                                    moz-do-not-send="true"><img
data-attrs="{"src":"https://substack-post-media.s3.amazonaws.com/public/images/de64b6e3-5236-4edd-97d4-2aa24726dd2a_1240x840.png","fullscreen":null,"imageSize":null,"height":840,"width":1240,"resizeWidth":478,"bytes":93776,"alt":null,"title":null,"type":"image/png","href":null,"belowTheFold":true,"topImage":false,"internalRedirect":null}"
                                      alt="" class=""
src="https://substackcdn.com/image/fetch/w_478,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fde64b6e3-5236-4edd-97d4-2aa24726dd2a_1240x840.png"
                                      style="-ms-interpolation-mode:
                                      bicubic; border: none !important;
                                      display: block; height: auto;
                                      margin: 0 auto; margin-bottom: 0;
                                      max-width: 100% !important;
                                      vertical-align: middle; width:
                                      auto !important;"
                                      moz-do-not-send="true" width="478"
                                      height="323.80645161290323"></a></td>
                                <td style="text-align: center;"><br>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                        </figure>
                      </div>
                      <ul style="margin-top: 0; padding: 0;">
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Potential relief for
                                immunocompromised</strong></em><span>.
                              AstraZeneca is </span><a
href="https://substack.com/redirect/028bca37-ed12-41af-a1b7-2fae32515fe0?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">on track</a><span>
                              for an Evushield replacement. Their Phase
                              III clinical trial is showing promising
                              results. An emergency use authorization
                              “could be here by the second half of this
                              year.”</span></p>
                        </li>
                      </ul>
                      <h4 class="header-with-anchor-widget"
                        style="-moz-appearance: optimizelegibility;
                        -moz-osx-font-smoothing: antialiased;
                        -webkit-appearance: optimizelegibility;
                        -webkit-font-smoothing: antialiased; appearance:
                        optimizelegibility; color: #404040; font-family:
                        'SF Compact Display', -apple-system,
                        BlinkMacSystemFont, 'Segoe UI', Roboto,
                        Helvetica, Arial, sans-serif, 'Apple Color
                        Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';
                        font-size: 1.125em; font-weight: bold;
                        line-height: 1.16em; margin: 1em 0 0.625em 0;
                        position: relative;">Interesting science updates</h4>
                      <ul style="margin-top: 0; padding: 0;">
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Changes in transmission. </strong></em><span>The
                              risk of household transmission is </span><a
href="https://substack.com/redirect/36f3da2e-53cc-4599-a5fa-438e669202e0?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">increasing </a><span>as
                              Omicron continues to mutate. In addition,
                              expect to get infected ~1 day quicker than
                              before (average 4 days). Infection risk
                              continues to be higher among unvaccinated
                              versus vaccinated people. </span></p>
                        </li>
                      </ul>
                      <div class="captioned-image-container-static"
                        style="font-size: 16px; line-height: 26px;
                        margin: 32px auto;">
                        <figure style="margin: 0 auto; width: 100%;">
                          <table class="image-wrapper"
                            data-component-name="Image2ToDOMStatic"
                            style="mso-padding-alt: 1em 0 1.6em;"
                            width="100%" cellspacing="0" cellpadding="0"
                            border="0">
                            <tbody>
                              <tr>
                                <td style="text-align: center;"><br>
                                </td>
                                <td class="content" style="text-align:
                                  center;" width="518" align="left"><a
                                    class="image-link" target="_blank"
href="https://substack.com/redirect/6fa31425-d5ae-4d5a-9169-acd274fae7cf?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                                    rel="" style="align-items: center;
                                    border: none; display: block;
                                    flex-direction: column; height:
                                    auto; margin: 0; padding: 0;
                                    position: relative; text-decoration:
                                    none; width: auto;"
                                    moz-do-not-send="true"><img
data-attrs="{"src":"https://substack-post-media.s3.amazonaws.com/public/images/dfbdd861-3b2f-4d40-9fcc-88426cdb0694_1240x426.png","fullscreen":null,"imageSize":null,"height":426,"width":1240,"resizeWidth":518,"bytes":63763,"alt":null,"title":null,"type":"image/png","href":null,"belowTheFold":true,"topImage":false,"internalRedirect":null}"
                                      alt="" class=""
src="https://substackcdn.com/image/fetch/w_518,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdfbdd861-3b2f-4d40-9fcc-88426cdb0694_1240x426.png"
                                      style="-ms-interpolation-mode:
                                      bicubic; border: none !important;
                                      display: block; height: auto;
                                      margin: 0 auto; margin-bottom: 0;
                                      max-width: 100% !important;
                                      vertical-align: middle; width:
                                      auto !important;"
                                      moz-do-not-send="true" width="518"
                                      height="177.95806451612904"></a></td>
                                <td style="text-align: center;"><br>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                        </figure>
                      </div>
                      <ul style="margin-top: 0; padding: 0;">
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Missed opportunity.</strong></em><span>
                              COVID-19 vaccinations rates among children
                              are abysmal. One study found that if we
                              reached flu vaccine coverage levels over
                              this past winter, we could have </span><a
href="https://substack.com/redirect/973fcb07-d933-46a3-b399-15089c7c4d67?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">prevented </a><span>10,019
                              pediatric hospitalizations and 5,448,694
                              days of school absence for COVID-19. </span><em>Better
                              luck next year? </em></p>
                        </li>
                        <li style="margin: 8px 0 0 32px;
                          mso-special-format: bullet;">
                          <p style="box-sizing: border-box; color:
                            #404040; font-size: 16px; line-height: 26px;
                            margin: 0; margin-bottom: 0; padding-left:
                            4px;"><em><strong>Risk of long COVID after
                                second infection.</strong></em><span>
                              Risk of long COVID decreases after second
                              infections, but is not zero. A new </span><a
href="https://substack.com/redirect/69182cfc-7122-49f5-8010-31f29b4a5658?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">preprint </a><span>found
                              the risk of long COVID after a second
                              infection is 1 in 40 for those over 16
                              years old and 1 in 165 for those under 16
                              years old. (As a </span><a
href="https://substack.com/redirect/b7e5282d-07c7-4f1c-8b59-de2bcb13cbb6?j=eyJ1IjoiYTEzdCJ9.fXnNfjqEHuJb90uhUC5MuKSqDSSONTVxMYyEVAne1uo"
                              rel="" style="color: #538cfa;
                              text-decoration: none;"
                              moz-do-not-send="true">comparison</a><span>,
                              the annual risk of getting into a car
                              accident is 1 in 30 and</span><strong> </strong><span>the
                              annual risk of permanent impairment is 1
                              in 700.)</span></p>
                        </li>
                      </ul>
                      <h4 class="header-with-anchor-widget"
                        style="-moz-appearance: optimizelegibility;
                        -moz-osx-font-smoothing: antialiased;
                        -webkit-appearance: optimizelegibility;
                        -webkit-font-smoothing: antialiased; appearance:
                        optimizelegibility; color: #404040; font-family:
                        'SF Compact Display', -apple-system,
                        BlinkMacSystemFont, 'Segoe UI', Roboto,
                        Helvetica, Arial, sans-serif, 'Apple Color
                        Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';
                        font-size: 1.125em; font-weight: bold;
                        line-height: 1.16em; margin: 1em 0 0.625em 0;
                        position: relative;">What’s next?</h4>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;">We are
                        in for a few quiet weeks (or months? who knows).
                        In June, we should have clarity on the fall
                        COVID-19 vaccine plan in the States. Stay tuned.
                      </p>
                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;">Love,
                        YLE</p>
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                      <p style="color: #404040; font-size: 16px;
                        line-height: 26px; margin: 0 0 20px 0;"><em>“Your
                          Local Epidemiologist (YLE)” is written by Dr.
                          Katelyn Jetelina, MPH PhD—an epidemiologist,
                          data scientist, wife, and mom of two little
                          girls. During the day she works at a
                          nonpartisan health policy think tank and is a
                          senior scientific consultant to a number of
                          organizations, including the CDC. At night she
                          writes this newsletter. Her main goal is to
                          “translate” the ever-evolving public health
                          science so that people will be well equipped
                          to make evidence-based decisions. This
                          newsletter is free thanks to the generous
                          support of fellow YLE community members. To
                          support this effort, subscribe below:</em></p>
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class="email-button-outline" style="border: 1px solid rgba(0, 0, 0,
                                                    .13); border-radius:
                                                    100000px; color:
                                                    #808080; display:
                                                    inline-block;
                                                    font-family: 'SF Pro
                                                    Text',
                                                    -apple-system,
                                                    ui-sans-serif,
                                                    BlinkMacSystemFont,
                                                    'Segoe UI', Roboto,
                                                    Helvetica, Arial,
                                                    sans-serif, 'Apple
                                                    Color Emoji', 'Segoe
                                                    UI Emoji', 'Segoe UI
                                                    Symbol'; font-size:
                                                    12px; font-weight:
                                                    500; line-height:
                                                    12px; padding: 9px
                                                    14px;
                                                    text-decoration:
                                                    none;
                                                    text-transform:
                                                    uppercase;"
                                                    moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Ficon%2FLucideComments%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2"
                                                      style="border:
                                                      none !important;
                                                      margin-right: 8px;
                                                      max-width: 18px;
                                                      min-height: 18px;
                                                      min-width: 18px;
                                                      vertical-align:
                                                      middle;" alt=""
                                                      class="icon"
                                                      moz-do-not-send="true"
                                                      width="18"
                                                      height="18"><span
class="email-button-text" style="vertical-align: middle;">Comment</span></a></td>
                                              </tr>
                                            </tbody>
                                          </table>
                                        </td>
                                        <td style="min-width: 8px"
                                          width="8"><br>
                                        </td>
                                        <td style="vertical-align:
                                          middle;">
                                          <table role="presentation"
                                            width="auto" cellspacing="0"
                                            cellpadding="0" border="0">
                                            <tbody>
                                              <tr>
                                                <td align="center"><a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly95b3VybG9jYWxlcGlkZW1pb2xvZ2lzdC5zdWJzdGFjay5jb20vcC9jYXRjaC11cC1xdWljay1jb3ZpZC0xOS1kMmI_dXRtX3NvdXJjZT1zdWJzdGFjayZ1dG1fbWVkaXVtPWVtYWlsJmFjdGlvbj1yZXN0YWNrLWNvbW1lbnQiLCJwIjoxMjMxNTg3NzIsInMiOjI4MTIxOSwiZiI6dHJ1ZSwidSI6NDY3OTkzLCJpYXQiOjE2ODUwMTM0NjksImV4cCI6MTY4NzYwNTQ2OSwiaXNzIjoicHViLTAiLCJzdWIiOiJsaW5rLXJlZGlyZWN0In0.t4_G6-Ge-PzIdmtCB-GV2gqsWudUgEAfBu100uLxp9E?&utm_source=substack&utm_medium=email"
class="email-button-outline" style="border: 1px solid rgba(0, 0, 0,
                                                    .13); border-radius:
                                                    100000px; color:
                                                    #808080; display:
                                                    inline-block;
                                                    font-family: 'SF Pro
                                                    Text',
                                                    -apple-system,
                                                    ui-sans-serif,
                                                    BlinkMacSystemFont,
                                                    'Segoe UI', Roboto,
                                                    Helvetica, Arial,
                                                    sans-serif, 'Apple
                                                    Color Emoji', 'Segoe
                                                    UI Emoji', 'Segoe UI
                                                    Symbol'; font-size:
                                                    12px; font-weight:
                                                    500; line-height:
                                                    12px; padding: 9px
                                                    14px;
                                                    text-decoration:
                                                    none;
                                                    text-transform:
                                                    uppercase;"
                                                    moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Ficon%2FNoteForwardIcon%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2"
                                                      style="border:
                                                      none !important;
                                                      margin-right: 8px;
                                                      max-width: 18px;
                                                      min-height: 18px;
                                                      min-width: 18px;
                                                      vertical-align:
                                                      middle;" alt=""
                                                      class="icon"
                                                      moz-do-not-send="true"
                                                      width="18"
                                                      height="18"><span
class="email-button-text" style="vertical-align: middle;">Restack</span></a></td>
                                              </tr>
                                            </tbody>
                                          </table>
                                        </td>
                                      </tr>
                                    </tbody>
                                  </table>
                                </td>
                                <td align="right">
                                  <table role="presentation"
                                    width="auto" cellspacing="0"
                                    cellpadding="0" border="0">
                                    <tbody>
                                      <tr>
                                      </tr>
                                    </tbody>
                                  </table>
                                </td>
                              </tr>
                            </tbody>
                          </table>
                        </td>
                      </tr>
                      <tr height="16">
                        <td style="font-size: 0px; line-height: 0;"
                          height="16"> </td>
                      </tr>
                    </tbody>
                  </table>
                  <div class="footer
                    frontend-email-shared-typed-module__footer--WmMp1"
                    style="color: #808080; font-size: 16px; line-height:
                    26px; padding: 24px 0; text-align: center;">
                    <div style="font-size: 16px; line-height: 26px;
                      padding-bottom: 24px;">
                      <p class="pencraft
                        frontend-pencraft-Box-module__reset--tAIEo
                        frontend-pencraft-Text-module__size-12--2onFT
                        frontend-pencraft-Text-module__color-secondary--XjVGl
                        frontend-pencraft-Text-module__reset--20JLV
                        small
                        frontend-email-shared-typed-module__meta--AAyPr"
                        style="color: #808080; font-family:
                        -apple-system, BlinkMacSystemFont, 'Segoe UI',
                        Roboto, Helvetica, Arial, sans-serif, 'Apple
                        Color Emoji', 'Segoe UI Emoji', 'Segoe UI
                        Symbol'; font-size: 12px; letter-spacing: 0;
                        line-height: 16px; margin: 0; padding-bottom: 0;
                        text-decoration: unset;">© 2023 <span>Your
                          Local Epidemiologist</span><br>
                        548 Market Street PMB 72296, San Francisco, CA
                        94104 <br>
                        <a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly95b3VybG9jYWxlcGlkZW1pb2xvZ2lzdC5zdWJzdGFjay5jb20vYWN0aW9uL2Rpc2FibGVfZW1haWw_dG9rZW49ZXlKMWMyVnlYMmxrSWpvME5qYzVPVE1zSW5CdmMzUmZhV1FpT2pFeU16RTFPRGMzTWl3aWFXRjBJam94TmpnMU1ERXpORFk1TENKbGVIQWlPakUyT0RjMk1EVTBOamtzSW1semN5STZJbkIxWWkweU9ERXlNVGtpTENKemRXSWlPaUprYVhOaFlteGxYMlZ0WVdsc0luMC5pRkN2dnhJdDZNQWZLamFTOC04WnBkM1lweTlsaG00NVBJM0ZnVVNpaHNrJmV4cGlyZXM9MzY1ZCIsInAiOjEyMzE1ODc3MiwicyI6MjgxMjE5LCJmIjp0cnVlLCJ1Ijo0Njc5OTMsImlhdCI6MTY4NTAxMzQ2OSwiZXhwIjoxNjg3NjA1NDY5LCJpc3MiOiJwdWItMCIsInN1YiI6ImxpbmstcmVkaXJlY3QifQ.82za668OqW1Mh2Me5qQiYqQvts3E3tu1FKbvLxm0_Ts?"
                          style="color: #538cfa; text-decoration: none;"
                          moz-do-not-send="true"><span style="color:
                            #808080; text-decoration: underline;">Unsubscribe</span></a></p>
                    </div>
                    <p
                      class="frontend-email-shared-typed-module__footerSection--9vwqp
                      small powered-by-substack" style="color: #808080;
                      font-family: -apple-system, BlinkMacSystemFont,
                      'Segoe UI', Roboto, Helvetica, Arial, sans-serif,
                      'Apple Color Emoji', 'Segoe UI Emoji', 'Segoe UI
                      Symbol'; font-size: 12px; line-height: 20px;
                      margin: 0; margin-top: 0; padding: 0 24px;
                      padding-bottom: 0;"><a
href="https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly9zdWJzdGFjay5jb20vc2lnbnVwP3V0bV9zb3VyY2U9c3Vic3RhY2smdXRtX21lZGl1bT1lbWFpbCZ1dG1fY29udGVudD1mb290ZXImdXRtX2NhbXBhaWduPWF1dG9maWxsZWQtZm9vdGVyJmZyZWVTaWdudXBFbWFpbD1tYW5ueUByYXRhZmlhcy5jb20iLCJwIjoxMjMxNTg3NzIsInMiOjI4MTIxOSwiZiI6dHJ1ZSwidSI6NDY3OTkzLCJpYXQiOjE2ODUwMTM0NjksImV4cCI6MTY4NzYwNTQ2OSwiaXNzIjoicHViLTAiLCJzdWIiOiJsaW5rLXJlZGlyZWN0In0.S0RMsP6ger8xU6Y2MOTyuLQIkLJXiPVWkhSpc_ytoi8?"
                        style="color: #538cfa; display: inline-block;
                        margin: 0 4px; text-decoration: none;"
                        moz-do-not-send="true"><img
src="https://substackcdn.com/image/fetch/w_270,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Fimg%2Femail%2Fpublish-button%402x.png"
srcset="https://substackcdn.com/image/fetch/w_135,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Fimg%2Femail%2Fpublish-button.png,
https://substackcdn.com/image/fetch/w_270,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Fimg%2Femail%2Fpublish-button%402x.png
                          2x,
https://substackcdn.com/image/fetch/w_405,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Fimg%2Femail%2Fpublish-button%403x.png
                          3x" alt="Start writing" style="border: none
                          !important; max-width: 550px; vertical-align:
                          middle;" moz-do-not-send="true" width="135"
                          height="40"></a></p>
                  </div>
                </div>
              </td>
              <td><br>
              </td>
            </tr>
          </tbody>
        </table>
        <img
src="https://mailgun.substack.com/api/v1/email/open?token=eyJtIjoiPDIwMjMwNTI1MTExNTA3LjMuMzAzOGZiOTI2ZjlkZGRmZEBtZy1kMS5zdWJzdGFjay5jb20-IiwidSI6NDY3OTkzLCJyIjoibWFubnlAcmF0YWZpYXMuY29tIiwiZCI6Im1nLWQxLnN1YnN0YWNrLmNvbSIsInAiOjEyMzE1ODc3MiwidCI6Im5ld3NsZXR0ZXIiLCJhIjoiZXZlcnlvbmUiLCJzIjoyODEyMTksImMiOiJwb3N0IiwiZiI6dHJ1ZSwicG9zaXRpb24iOiJib3R0b20iLCJpYXQiOjE2ODUwMTM0NzAsImV4cCI6MTY4NzYwNTQ3MCwiaXNzIjoicHViLTAiLCJzdWIiOiJlbyJ9.B3iNGRcSiPfmPvsP0IWexeqyeXRqj7Z_L97sbv6LfRo"
          alt="" style="height:1px !important;width:1px
          !important;border-width:0 !important;margin-top:0
          !important;margin-bottom:0 !important;margin-right:0
          !important;margin-left:0 !important;padding-top:0
          !important;padding-bottom:0 !important;padding-right:0
          !important;padding-left:0 !important;" moz-do-not-send="true"
          width="1" height="1" border="0"><img alt=""
src="https://email.mg-d1.substack.com/o/eJxEkEuK7SAURUdz7b3gJ5qk4VjCUU_ypPwEPVaR2Rf3A9VdGxaL7YHwrO22V-3EglWb46s3DK0wq-ZCzcvGMENM-4kFGxCGHehv5Zqv7L_1s4F5mY1apfMSnQ5aS4GwGAPKoGTRSi4V11ILITRfJjUprtbDbdIcWwjhCI-Z5_NfEFMfrhP4r8nXzGLfj4avBEttIHuW7jBCxOLR4je2u5YPjsEKqYRel0W-Cd0X2oI_PSERNnYNt_ua8yiR7h0LuIThIx4uRQ8Ua3mK5Cqk2FizGUq5HzNvQHBE6K-sPlyoGWKxdx0tVQ8Jrxgwx5rqGTsxen86OranbjbLtqnfAAAA__8htnuK"
          moz-do-not-send="true" width="1px" height="1px">
        <div id="DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2"><br>
          <table style="border-top: 1px solid #D3D4DE;">
            <tbody>
              <tr>
                <td style="width: 55px; padding-top: 13px;"><a
href="http://www.avg.com/email-signature?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient"
                    target="_blank" moz-do-not-send="true"><img
src="https://s-install.avcdn.net/ipm/preview/icons/icon-envelope-tick-green-avg-v1.png"
                      alt="" style="width: 46px; height: 29px;"
                      moz-do-not-send="true" width="46" height="29"></a></td>
                <td style="width: 470px; padding-top: 12px; color:
                  #41424e; font-size: 13px; font-family: Arial,
                  Helvetica, sans-serif; line-height: 18px;">Virus-free.<a
href="http://www.avg.com/email-signature?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient"
                    target="_blank" style="color: #4453ea;"
                    moz-do-not-send="true">www.avg.com</a></td>
              </tr>
            </tbody>
          </table>
          <a href="#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2" width="1"
            height="1" moz-do-not-send="true"> </a></div>
      </div>
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